Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5846265 | 0.99 | SIGMAR1 (0.59) | SIGMAR1PARP1DRD2DRD4DRD3 | |
| SCHEMBL5846325 | 0.88 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL5846965 | 0.88 | SIGMAR1 (0.62) | SIGMAR1PARP1DRD2 | |
| SCHEMBL5846526 | 0.88 | SIGMAR1 (0.62) | SIGMAR1PARP1DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL5847835 | 0.86 | SIGMAR1 (0.61) | SIGMAR1PARP1DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL5846857 | 0.86 | SIGMAR1 (0.47) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5847091 | 0.86 | SIGMAR1 (0.61) | SIGMAR1PARP1DRD2 | |
| SCHEMBL6159703 | 0.83 | SIGMAR1 (0.62) | SIGMAR1PARP1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL5846250 | 0.82 | SIGMAR1 (0.60) | SIGMAR1PARP1DRD2DRD4DRD3 | |
| SCHEMBL5846286 | 0.78 | SIGMAR1 (0.61) | SIGMAR1PARP1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721455-B9 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2005-04-20 | — | — | EP | claimed |
| EP-0721455-B1 | TETRAHYDROPYRIDINE-(OR 4-HYDROXYPIPERIDINE)ALKYLAZOLES HAVING AN AFFINITY FOR SIGMA AND/OR 5HT1A RECEPTORS | ESTEVE LABOR DR (ES) | 2002-12-11 | — | — | EP | claimed |