Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 20/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6164503 | 0.94 | DRD4 (0.89) | DRD4DRD2 | |
| SCHEMBL6160027 | 0.87 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL6161766 | 0.84 | DRD4 (1.00) | DRD4DRD2 | |
| Oxalic Acid SCHEMBL7648434 | 0.83 | DRD4 (0.89) | DRD4DRD2 | |
| Oxalic Acid SCHEMBL6165259 | 0.82 | DRD4 (0.88) | DRD4DRD2 | |
| SCHEMBL6160762 | 0.81 | DRD4 (1.00) | DRD4DRD2 | |
| Oxalic Acid SCHEMBL6163601 | 0.79 | DRD4 (0.89) | DRD4DRD2 | |
| SCHEMBL25396399 | 0.79 | DRD4 (0.85) | DRD4 | |
| SCHEMBL6162328 | 0.79 | DRD4 (0.85) | DRD4 | |
| SCHEMBL6164051 | 0.78 | DRD4 (1.00) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920423-B1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH AS (DK) | 2005-01-26 | — | — | EP | claimed |
| EP-0920423-B1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH AS (DK) | 2005-01-26 | — | — | EP | disclosed |
| US-6479491-B1 | USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, ESPECIALLY PSYCHOTIC DISORDERS SUCH AS SCHIZOPHRENIA | NEUROSEARCH A/S (DK) | 2002-11-12 | — | — | US | disclosed |