SCHEMBL6162328

SCHEMBL6162328

CCOc1ccccc1OCC1CN(Cc2ccccc2)CCO1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 19/20 0.85
HRH3 Q9Y5N1 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25396399 1.00 DRD4 (0.85) DRD4HRH3
Bromide SCHEMBL30589863 0.99 DRD4 (0.83) DRD4HRH3
Bromide SCHEMBL30589855 0.99 DRD4 (0.83) DRD4HRH3
Hydrochloric Acid SCHEMBL25397740 0.99 DRD4 (0.83) DRD4HRH3
SCHEMBL6164051 0.92 DRD4 (1.00) DRD4
Oxalic Acid SCHEMBL6162010 0.88 DRD4 (0.88) DRD4
SCHEMBL6162444 0.86 DRD4 (1.00) DRD4
SCHEMBL4502566 0.85 DRD4 (0.74) DRD4
Oxalic Acid SCHEMBL7648434 0.85 DRD4 (0.89) DRD4
SCHEMBL16976478 0.85 DRD4 (0.64) DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078098-A1 PROCESS OF MAKING DERIVATIVES OF SUBSTITUTED MORPHOLINES SUPERNUS PHARMACEUTICALS, INC. (US) 2026-03-19 US disclosed
US-20260062395-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES CURIA SPAIN S A U (ES) 2026-03-05 US disclosed
EP-4565571-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES CURIA SPAIN, S.A.U. (ES) 2025-06-11 EP disclosed
CN-119768395-A Processes and intermediates for the preparation of viloxazine and other 2-substituted morpholine derivatives 库里亚西班牙公司 2025-04-04 CN disclosed
EP-4493550-A1 PROCESS OF MAKING DERIVATIVES OF SUBSTITUTED MORPHOLINES Supernus Pharmaceuticals, Inc. (US) 2025-01-22 EP disclosed
US-11964951-B2 Process of making derivatives of substituted morpholines SUPERNUS PHARMACEUTICALS, INC. (US) 2024-04-23 US disclosed
WO-2024028423-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES CURIA SPAIN, S.A.U. (ES) 2024-02-08 WO disclosed
EP-4317141-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES Curia Spain S.A.U. (ES) 2024-02-07 EP disclosed
US-20230357173-A1 PROCESS OF MAKING DERIVATIVES OF SUBSTITUTED MORPHOLINES SUPERNUS PHARMACEUTICALS, INC. (US) 2023-11-09 US disclosed
WO-2023177845-A1 PROCESS OF MAKING DERIVATIVES OF SUBSTITUTED MORPHOLINES SUPERNUS PHARMACEUTICALS, INC. (US) 2023-09-21 WO disclosed
US-9403783-B2 Methods for producing viloxazine salts and novel polymorphs thereof SUPERNUS PHARMACEUTICALS, INC. (US) 2016-08-02 US disclosed
US-9403783-B2 Methods for producing viloxazine salts and novel polymorphs thereof SUPERNUS PHARMACEUTICALS, INC. (US) 2016-08-02 US disclosed
EP-2558437-B1 METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF SUPERNUS PHARMACEUTICALS INC (US) 2015-08-05 EP disclosed
US-20150126735-A1 METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF SUPERNUS PHARMACEUTICALS INC. (US) 2015-05-07 US disclosed
US-20110251198-A1 METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF SUPERNUS PHARMACEUTICALS INC. (US) 2011-10-13 US disclosed
EP-0920423-B1 DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS NEUROSEARCH AS (DK) 2005-01-26 EP disclosed
US-6479491-B1 USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, ESPECIALLY PSYCHOTIC DISORDERS SUCH AS SCHIZOPHRENIA NEUROSEARCH A/S (DK) 2002-11-12 US disclosed
US-6207662-B1 USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOTIC DISORDERS SUCH AS SCHIZOPHRENIA NEUROSEARCH A/S (DK) 2001-03-27 US disclosed
EP-0920423-A1 DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS NEUROSEARCH A/S (DK) 1999-06-09 EP disclosed
WO-1998007710-A1 DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS NEUROSEARCH A/S (DK) 1998-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11964951-B2 Process of making derivatives of substituted morpholines UGT2B7, CYP3A7, CYP3A4 DRD4 160/4885HRH3 3933/4885
US-20260078098-A1 PROCESS OF MAKING DERIVATIVES OF SUBSTITUTED MORPHOLINES HTR2C, SLC6A2, HTR1D DRD4 64/4885HRH3 411/4885
US-20230357173-A1 PROCESS OF MAKING DERIVATIVES OF SUBSTITUTED MORPHOLINES UGT2B7, CYP3A7, CYP3A4 DRD4 160/4885HRH3 3933/4885
US-20260062395-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES OGFRL1, SALL4, OGFR DRD4 2218/4885HRH3 2845/4885
US-20150126735-A1 METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF CYP3A5, VIL1, CYP3A4 DRD4 722/4885HRH3 621/4885
US-20110251198-A1 METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF CYP3A5, VIL1, CYP3A4 DRD4 722/4885HRH3 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.