Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161965 | 1.00 | MAPK1 (0.48) | MAPK1CYP3A4CALCRLKMT2AOPRM1 | |
| SCHEMBL6163907 | 0.85 | CALCRL (0.49) | MAPK1CYP3A4CALCRLKMT2AYAP1 | |
| SCHEMBL6163334 | 0.84 | CALCRL (0.67) | MAPK1CYP3A4CALCRL | |
| SCHEMBL6163332 | 0.84 | CALCRL (0.67) | MAPK1CYP3A4CALCRL | |
| SCHEMBL6162890 | 0.83 | MAPK1 (0.57) | MAPK1KMT2AOPRM1OGFRL1OPRD1 | |
| SCHEMBL6162897 | 0.83 | MAPK1 (0.57) | MAPK1KMT2AOPRM1OGFRL1OPRD1 | |
| SCHEMBL8412850 | 0.80 | CALCRL (0.50) | CYP3A4CALCRLKMT2ACAPN1CTSB | |
| SCHEMBL6165709 | 0.80 | CALCRL (0.50) | CYP3A4CALCRLKMT2ACAPN1CTSB | |
| SCHEMBL6162914 | 0.80 | MAPK1 (0.62) | MAPK1KMT2AYAP1CAPN1CTSB | |
| SCHEMBL6162909 | 0.80 | MAPK1 (0.62) | MAPK1KMT2AYAP1CAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |