Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162897 | 1.00 | MAPK1 (0.57) | MAPK1KMT2AMAPTNPSR1MEN1 | |
| SCHEMBL6165473 | 0.85 | KMT2A (0.49) | MAPK1KMT2AMAPTNPSR1MEN1 | |
| SCHEMBL6165477 | 0.85 | KMT2A (0.49) | MAPK1KMT2AMAPTNPSR1MEN1 | |
| SCHEMBL6163831 | 0.84 | CALCRL (0.47) | KMT2AOPRM1OGFRL1OPRD1OPRK1 | |
| SCHEMBL6163841 | 0.84 | CALCRL (0.47) | KMT2AOPRM1OGFRL1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6163666 | 0.83 | CALCRL (0.47) | KMT2AOPRM1OGFRL1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL6163658 | 0.83 | CALCRL (0.47) | KMT2AOPRM1OGFRL1OPRD1OPRK1 | |
| SCHEMBL6161965 | 0.83 | MAPK1 (0.48) | MAPK1KMT2APABPC1ALDH1A1STS | |
| SCHEMBL6161971 | 0.83 | MAPK1 (0.48) | MAPK1KMT2APABPC1ALDH1A1STS | |
| SCHEMBL8412850 | 0.82 | CALCRL (0.50) | KMT2AMEN1FPR2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |