Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MOK | Q9UQ07 | 3/20 | 0.50 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162317 | 0.83 | POLB (0.74) | POLBMEN1KMT2ATRPV1MOK | |
| SCHEMBL6162171 | 0.80 | POLB (0.58) | POLBMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL6163628 | 0.78 | POLB (0.74) | POLBMEN1KMT2ATRPV1KDM4E | |
| SCHEMBL10761683 | 0.77 | POLB (0.73) | POLBMEN1KMT2AKDM4EHTT | |
| SCHEMBL6167121 | 0.76 | TRPV1 (0.57) | POLBKMT2ATRPV1MOKPLAUR | |
| SCHEMBL6163447 | 0.76 | TRPV1 (0.54) | POLBKMT2ATRPV1MOKPLAUR | |
| SCHEMBL6165849 | 0.73 | POLB (0.67) | POLBMEN1KMT2AMOKKDM4E | |
| SCHEMBL6164179 | 0.73 | POLB (0.67) | POLBMEN1KMT2AMOKKDM4E | |
| SCHEMBL6164135 | 0.73 | TRPV1 (0.52) | POLBTRPV1PLAURHPGDCYP2C9 | |
| SCHEMBL6164125 | 0.72 | POLB (0.65) | POLBMEN1KMT2AMOKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |