Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLAUR | Q03405 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167121 | 0.90 | TRPV1 (0.57) | TRPV1POLBAURKACYP2C9KMT2A | |
| SCHEMBL6164543 | 0.85 | POLB (0.69) | TRPV1POLBCYP2C9KMT2ARAB9A | |
| SCHEMBL6164135 | 0.84 | TRPV1 (0.52) | TRPV1POLBAURKACYP2C9PLAUR | |
| SCHEMBL6167175 | 0.81 | RAB9A (0.50) | TRPV1AURKAPLAURRAB9A | |
| SCHEMBL6165844 | 0.81 | RAB9A (0.50) | TRPV1AURKAPLAURRAB9A | |
| SCHEMBL6163701 | 0.81 | RAB9A (0.50) | TRPV1AURKAPLAURRAB9A | |
| SCHEMBL6163443 | 0.80 | POLB (0.53) | POLBCYP2C9KMT2ARAB9ATDP1 | |
| SCHEMBL6166298 | 0.76 | POLB (0.66) | POLBCYP2C9KMT2ARAB9ATDP1 | |
| SCHEMBL6162175 | 0.76 | POLB (0.53) | TRPV1POLBCYP2C9KMT2APLAUR | |
| SCHEMBL6163311 | 0.76 | POLB (0.65) | TRPV1POLBCYP2C9KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337523-B1 | 2,4-SUBSTITUTED PYRIDINE DERIVATIVES | NEUROGEN CORP (US) | 2005-10-19 | — | — | EP | claimed |