Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161358 | 0.91 | GRIN1 (0.59) | MEN1KMT2ALMNAMAPTGRIN1 | |
| SCHEMBL6163800 | 0.85 | GRIN1 (0.62) | MEN1KMT2ALMNAMAPTGRIN1 | |
| SCHEMBL8546472 | 0.80 | GRIN1 (0.60) | MEN1KMT2ALMNAMAPTGRIN1 | |
| SCHEMBL8546005 | 0.79 | GRIN1 (0.55) | MEN1KMT2ALMNAMAPTGRIN1 | |
| SCHEMBL6162014 | 0.79 | GRIN1 (0.54) | MEN1KMT2ALMNAMAPTGRIN1 | |
| SCHEMBL6161379 | 0.77 | GRIN1 (0.51) | MEN1KMT2ALMNAMAPTGRIN1 | |
| SCHEMBL8109896 | 0.76 | GRIN1 (0.69) | MEN1KMT2ALMNAMAPTGRIN1 | |
| SCHEMBL6161788 | 0.76 | GRIN1 (0.54) | MEN1KMT2ALMNAMAPTGRIN1 | |
| Besonprodil SCHEMBL29388542 | 0.76 | GRIN1 (0.66) | MEN1KMT2ALMNAMAPTGRIN1 | |
| Besonprodil SCHEMBL2257896 | 0.76 | GRIN1 (0.66) | MEN1KMT2ALMNAMAPTGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089735-B1 | 4-BENZYL PIPERIDINE ALKYLSULFOXIDE HETEROCYCLES AND THEIR USE AS SUBTYPE-SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-06-08 | — | — | EP | claimed |
| US-20030004187-A1 | Method for preventing dyskinesias | WARNER-LAMBERT COMPANY LLC | 2003-01-02 | — | — | US | claimed |
| EP-1254661-A1 | Method for preventing dyskinesias with selective NMDA-Antagonists | WARNER-LAMBERT COMPANY (US) | 2002-11-06 | — | — | EP | claimed |
| US-6284774-B1 | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | WARNER-LAMBERT COMPANY | 2001-09-04 | — | — | US | claimed |
| EP-1089735-B1 | 4-BENZYL PIPERIDINE ALKYLSULFOXIDE HETEROCYCLES AND THEIR USE AS SUBTYPE-SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20030004187-A1 | Method for preventing dyskinesias | WARNER-LAMBERT COMPANY LLC | 2003-01-02 | — | — | US | disclosed |
| EP-1254661-A1 | Method for preventing dyskinesias with selective NMDA-Antagonists | WARNER-LAMBERT COMPANY (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6284774-B1 | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | WARNER-LAMBERT COMPANY | 2001-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004187-A1 | Method for preventing dyskinesias | GRIN2B, GRIN2A, GRIN3A | MEN1 4669/4885KMT2A 244/4885LMNA 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.