Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872814 | 0.90 | MEN1 (0.47) | GRIN1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8546732 | 0.90 | MEN1 (0.47) | GRIN1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8548361 | 0.90 | MEN1 (0.47) | GRIN1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8546790 | 0.86 | GRIN2B (0.54) | GRIN1MEN1KMT2AGRIN2BGRIN2D | |
| SCHEMBL8545088 | 0.85 | GRIN1 (0.64) | GRIN1MEN1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL8541316 | 0.83 | MEN1 (0.47) | GRIN1MEN1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL8591425 | 0.83 | MEN1 (0.47) | GRIN1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8546472 | 0.81 | GRIN1 (0.60) | GRIN1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6162227 | 0.79 | MEN1 (0.56) | GRIN1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8542871 | 0.77 | GRIN2B (0.54) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |