SCHEMBL6162381

SCHEMBL6162381

COC1(OC)CCC(C(C)(C)C)CC1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
AQP3 Q92482 1/20 0.30
ATM Q13315 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7592187 0.87 ALDH1A1 (0.31) ALDH1A1MEN1CYP2C9CYP2C19KMT2A
SCHEMBL20594351 0.78 ALDH1A1 (0.37) ALDH1A1MEN1CYP2C9CYP2C19KMT2A
SCHEMBL6360972 0.78
SCHEMBL2486985 0.78 ALDH1A1 (0.33) ALDH1A1CYP2C9CYP2C19USP2GAA
SCHEMBL4805438 0.75 KDM4E (0.32) ALDH1A1CYP2C9CYP2C19GAACYP1A2
SCHEMBL10706815 0.75 ALDH1A1 (0.31) ALDH1A1USP2GAAMAPTTDP1
SCHEMBL7595344 0.74
SCHEMBL2125652 0.74 ALDH1A1 (0.36) ALDH1A1USP2GAAMAPTTDP1
SCHEMBL24132476 0.73 CYP1A2 (0.48) ALDH1A1MEN1CYP2C9CYP2C19KMT2A
Methoxymethane SCHEMBL21931862 0.71 ALDH1A1 (0.35) ALDH1A1MEN1CYP2C9CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103937328-B Cycylohexyl-mannitol diketal derivatives as vehicle modifiers and gelators 施乐公司 2017-02-08 CN disclosed
EP-0893442-B1 LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES SHIONOGI & CO (JP) 2005-01-12 EP disclosed
US-6054591-A LYMPHOTROPIC ANTI-AIDS AGENT SHIONOGI & CO., LTD. (JP) 2000-04-25 US disclosed
EP-0893442-A1 LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES SHIONOGI & CO., LTD. (JP) 1999-01-27 EP disclosed