Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | KHK | P50053 | 2/20 | 0.47 |
| ▸ | QDPR | P09417 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204336 | 0.89 | SIGMAR1 (0.67) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| SCHEMBL3032622 | 0.87 | HTR2C (0.54) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| SCHEMBL4789465 | 0.79 | HTR2C (0.66) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| SCHEMBL28015195 | 0.79 | HTR2C (0.60) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| Hydrochloric Acid SCHEMBL9532611 | 0.78 | HTR2C (0.67) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| SCHEMBL532892 | 0.77 | HTR2C (0.66) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| SCHEMBL6278676 | 0.76 | HTR2C (0.57) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| Hydrochloric Acid SCHEMBL730625 | 0.76 | HTR2C (0.67) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| SCHEMBL22144414 | 0.75 | HTR2C (0.56) | HTR2CSIGMAR1KHKQDPRHTR6 | |
| SCHEMBL6160755 | 0.74 | HTR2C (0.47) | HTR2CSIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |