Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 17/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 16/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162542 | 1.00 | ITGA4 (0.46) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL26547102 | 0.99 | ITGA4 (0.46) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL4671585 | 0.99 | ITGA4 (0.46) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL4671581 | 0.99 | ITGA4 (0.46) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL6162561 | 0.99 | ITGA4 (0.46) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL6163474 | 0.93 | ITGA4 (0.41) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL6163467 | 0.93 | ITGA4 (0.41) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL6162548 | 0.93 | ITGA4 (0.40) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL6166269 | 0.92 | ITGB1 (0.40) | ITGA4ITGB1CHEK1MEN1MAPT | |
| SCHEMBL6166262 | 0.92 | ITGB1 (0.40) | ITGA4ITGB1CHEK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373249-B1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTIINFLAMATORY AGENT | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| EP-1373249-A1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTINFLAMATORY AGENT | Aventis Pharma Deutschland GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002072573-A1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTINFLAMATORY AGENT. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-09-19 | — | — | WO | disclosed |