Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158968 | 0.92 | CCKBR (0.54) | CCKBR | |
| SCHEMBL6160706 | 0.88 | — | — | |
| SCHEMBL6160233 | 0.86 | CCKBR (0.67) | CCKBREPHX2PIK3CDAKT1PIK3CA | |
| SCHEMBL6159360 | 0.85 | CCKBR (0.54) | CCKBR | |
| SCHEMBL6161003 | 0.80 | CCKBR (0.73) | CCKBR | |
| SCHEMBL6160142 | 0.79 | CCKBR (0.58) | CCKBR | |
| SCHEMBL7682427 | 0.79 | — | — | |
| SCHEMBL6159688 | 0.77 | CCKBR (0.74) | CCKBR | |
| SCHEMBL7524223 | 0.77 | — | — | |
| SCHEMBL6163793 | 0.76 | CCKBR (0.50) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |