Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 4/20 | 0.72 |
| ▸ | TGM2 | P21980 | 4/20 | 0.72 |
| ▸ | TGM1 | P22735 | 4/20 | 0.72 |
| ▸ | CCR8 | P51685 | 2/20 | 0.53 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870031 | 0.84 | F13A1 (0.72) | F13A1TGM2TGM1CCR8CA1 | |
| SCHEMBL1869832 | 0.84 | TGM2 (1.00) | F13A1TGM2TGM1 | |
| SCHEMBL1868875 | 0.84 | TGM2 (1.00) | F13A1TGM2TGM1 | |
| SCHEMBL1868878 | 0.84 | TGM2 (1.00) | F13A1TGM2TGM1 | |
| SCHEMBL1843035 | 0.82 | SMN1; SMN2 (0.53) | F13A1TGM2TGM1SMN1; SMN2NPC1 | |
| SCHEMBL7401800 | 0.81 | F13A1 (0.72) | F13A1TGM2TGM1SMN1; SMN2NPC1 | |
| SCHEMBL1872545 | 0.80 | F13A1 (0.67) | F13A1TGM2TGM1CCR8SMN1; SMN2 | |
| SCHEMBL3615713 | 0.80 | SMN1; SMN2 (0.51) | F13A1TGM2TGM1SMN1; SMN2NPC1 | |
| SCHEMBL8788495 | 0.80 | SMN1; SMN2 (0.51) | F13A1TGM2TGM1SMN1; SMN2NPC1 | |
| SCHEMBL3789109 | 0.80 | SMN1; SMN2 (0.51) | F13A1TGM2TGM1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |