Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 19/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162301 | 1.00 | DRD4 (0.67) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6165547 | 1.00 | DRD4 (0.67) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6165562 | 0.91 | DRD4 (0.60) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13840030 | 0.88 | DRD4 (0.53) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8327024 | 0.86 | DRD4 (0.65) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4228489 | 0.86 | DRD4 (0.65) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6162202 | 0.86 | DRD4 (0.67) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6226338 | 0.86 | DRD4 (0.67) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL735729 | 0.86 | DRD4 (0.73) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2304936 | 0.86 | DRD4 (0.73) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235483-B1 | CIS-JASMONE AS SEMIOCHEMICAL | PLANT BIOSCIENCE LTD (GB) | 2005-02-16 | — | — | EP | disclosed |
| EP-0920423-B1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH AS (DK) | 2005-01-26 | — | — | EP | disclosed |
| US-20030109586-A1 | Semiochemical | PLANT BIOSCIENCE LIMITED (GB) | 2003-06-12 | — | — | US | disclosed |
| US-6479491-B1 | USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, ESPECIALLY PSYCHOTIC DISORDERS SUCH AS SCHIZOPHRENIA | NEUROSEARCH A/S (DK) | 2002-11-12 | — | — | US | disclosed |
| EP-1235483-A2 | CIS-JASMONE AS SEMIOCHEMICAL | BTG INTERNATIONAL LIMITED (GB) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001041568-A2 | CIS-JASMONE AS SEMIOCHEMICAL | BTG INTERNATIONAL LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |
| US-6207662-B1 | USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOTIC DISORDERS SUCH AS SCHIZOPHRENIA | NEUROSEARCH A/S (DK) | 2001-03-27 | — | — | US | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0920423-A1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH A/S (DK) | 1999-06-09 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| WO-1998007710-A1 | DISUBSTITUTED MORPHOLINE, OXAZEPINE OR THIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROSEARCH A/S (DK) | 1998-02-26 | — | — | WO | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |