Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 18/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | DRD3 | P35462 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304936 | 1.00 | DRD4 (0.73) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7696047 | 1.00 | DRD4 (0.73) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Oxalic Acid SCHEMBL27081684 | 0.93 | DRD4 (0.64) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3443710 | 0.91 | DRD4 (0.61) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Fumaric Acid SCHEMBL27083012 | 0.89 | DRD4 (0.60) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9385194 | 0.88 | DRD4 (0.78) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13319146 | 0.87 | DRD4 (0.73) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8291789 | 0.87 | DRD4 (0.73) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5748888 | 0.87 | DRD4 (0.73) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27692703 | 0.86 | DRD4 (0.63) | DRD4CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062395-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | CURIA SPAIN S A U (ES) | 2026-03-05 | — | — | US | claimed |
| EP-4565571-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | CURIA SPAIN, S.A.U. (ES) | 2025-06-11 | — | — | EP | claimed |
| CN-119768395-A | Processes and intermediates for the preparation of viloxazine and other 2-substituted morpholine derivatives | 库里亚西班牙公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2024028423-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | CURIA SPAIN, S.A.U. (ES) | 2024-02-08 | — | — | WO | claimed |
| EP-4317141-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | Curia Spain S.A.U. (ES) | 2024-02-07 | — | — | EP | claimed |
| EP-4731223-A1 | MORPHOLINE AND 1,4-OXAZEPANE COMPOUNDS AND ITS USE IN THERAPY | Universitat De Barcelona (ES) | 2026-04-29 | — | — | EP | disclosed |
| US-20260062395-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | CURIA SPAIN S A U (ES) | 2026-03-05 | — | — | US | disclosed |
| EP-4565571-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | CURIA SPAIN, S.A.U. (ES) | 2025-06-11 | — | — | EP | disclosed |
| CN-119768395-A | Processes and intermediates for the preparation of viloxazine and other 2-substituted morpholine derivatives | 库里亚西班牙公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024261340-A1 | MORPHOLINE AND 1,4-OXAZEPANE COMPOUNDS AND ITS USE IN THERAPY | UNIVERSITAT DE BARCELONA (ES) | 2024-12-26 | — | — | WO | disclosed |
| US-20240101549-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | US | disclosed |
| WO-2024028423-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | CURIA SPAIN, S.A.U. (ES) | 2024-02-08 | — | — | WO | disclosed |
| US-4748175-A | Pyrimido[5,4-B][1,4]oxazine derivatives and pharmaceutical compositions containing them | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1988-05-31 | — | — | US | disclosed |
| EP-0266576-A2 | 1-Tert-alkyl-substituted naphthyridine and quinoline carboxylic acids as antibacterial agents | Bristol-Myers Squibb Company (US) | 1988-05-11 | — | — | EP | disclosed |
| WO-1988002627-A1 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-04-21 | — | — | WO | disclosed |
| EP-0243959-A1 | Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-04 | — | — | EP | disclosed |
| CN-86108914-A | Process for preparing pyrimido [5, 4-b ] [1, 4] oxazine derivatives and pharmaceutical agents containing the same | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-09-30 | — | — | CN | disclosed |
| EP-0228094-A2 | Pyrimido[5,4-b][1,4]oxazine derivatives, process for their preparation, medicament containing them and intermediate pyrimido[5,4-b][1,4]oxazine derivatives | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1987-07-08 | — | — | EP | disclosed |
| US-4152434-A | ANTIDEPRESSANTS | HEXACHIMIE (FR) | 1979-05-01 | — | — | US | disclosed |
| US-4122175-A | ANTIDEPRESSANTS | HEXACHIMIE (FR) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101549-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES | FAP, PREP, CTRL | DRD4 4803/4885CYP1A2 1877/4885CYP3A4 1674/4885 |
| US-20260062395-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF VILOXAZINE AND OTHER 2-SUBSTITUTED MORPHOLINE DERIVATIVES | OGFRL1, SALL4, OGFR | DRD4 2218/4885CYP1A2 1300/4885CYP3A4 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.