Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450091 | 0.81 | RAB9A (1.00) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL3508351 | 0.80 | RAB9A (0.73) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL11208401 | 0.77 | RAB9A (0.68) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL5010479 | 0.76 | RAB9A (0.66) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL5358232 | 0.76 | RAB9A (0.66) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL9203037 | 0.76 | RAB9A (0.79) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL360146 | 0.76 | RAB9A (0.79) | RAB9AKMT2AGAAALDH1A1PKM | |
| P-Tolyl Dimethylcarbamate SCHEMBL360147 | 0.74 | RAB9A (0.83) | RAB9AKMT2AGAAALDH1A1PKM | |
| 4-Chlorophenyl Dimethylcarbamate SCHEMBL11300470 | 0.72 | RAB9A (0.79) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL9301148 | 0.72 | RAB9A (0.79) | RAB9AKMT2AGAAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549622-A1 | SULFONYLBENZODIAZEPINONE ACETAMIDES AS BRADYKININ ANTAGONISTS | Elian Pharmaceuticals Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033436-A1 | SULFONYLBENZODIAZEPINONE ACETAMIDES AS BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC (US) | 2004-04-22 | — | — | WO | disclosed |