Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954475 | 0.82 | CA12 (0.45) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL3010654 | 0.79 | CA12 (0.49) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL2998053 | 0.79 | MEN1 (0.48) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL3012558 | 0.71 | CES1 (0.65) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL30519490 | 0.71 | CES1 (0.65) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL30498849 | 0.66 | ALDH1A1 (0.58) | CA12CA9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL29054304 | 0.66 | ALDH1A1 (0.58) | CA12CA9ALDH1A1MAPTCYP1A2 | |
| SCHEMBL9618341 | 0.65 | CA12 (0.65) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL13607734 | 0.65 | PARP1 (0.40) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11181448 | 0.65 | KDM4E (0.79) | CA12CA9ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977545-B1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | HENKEL KGAA (DE) | 2005-02-16 | — | — | EP | claimed |
| EP-0977545-A1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-02-09 | — | — | EP | claimed |
| WO-1998047472-A1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-10-29 | — | — | WO | claimed |