SCHEMBL6163319

SCHEMBL6163319

CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCc2ccccc2C1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 10/20 0.56
OPRM1 P35372 1/20 0.56
ACE P12821 1/20 0.52
BCHE P06276 1/20 0.49
PKM P14618 1/20 0.49
KMT2A Q03164 1/20 0.48
MMP2 P08253 2/20 0.47
MMP9 P14780 2/20 0.47
MMP8 P22894 2/20 0.47
GABRA1 P14867 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
CYP3A4 P08684 1/20 0.46
UGCG Q16739 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6163306 1.00 GHSR (0.56) GHSROPRM1ACEBCHEPKM
Hydrochloric Acid SCHEMBL6160468 0.99 GHSR (0.55) GHSROPRM1ACEBCHEPKM
Hydrochloric Acid SCHEMBL6159951 0.99 GHSR (0.55) GHSROPRM1ACEBCHEPKM
Hydrochloric Acid SCHEMBL6162247 0.91 GHSR (0.51) GHSROPRM1ACEPKMMMP2
Hydrochloric Acid SCHEMBL6162252 0.91 GHSR (0.51) GHSROPRM1ACEPKMMMP2
Hydrochloric Acid SCHEMBL6160507 0.89 GHSR (0.49) GHSROPRM1ACEPKMKMT2A
SCHEMBL6165098 0.89 GHSR (0.49) GHSROPRM1ACEPKMKMT2A
Hydrochloric Acid SCHEMBL6160499 0.89 GHSR (0.49) GHSROPRM1ACEPKMKMT2A
SCHEMBL6165094 0.89 GHSR (0.49) GHSROPRM1ACEPKMKMT2A
SCHEMBL6166003 0.89 GHSR (0.49) GHSROPRM1ACEPKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed