Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281523 | 0.82 | FFAR1 (0.51) | FFAR1FFAR4MAOBGLAADAMTS4 | |
| SCHEMBL17784702 | 0.80 | GLA (0.49) | FFAR1FFAR4MAOBGLAMAOA | |
| SCHEMBL1228846 | 0.75 | GLA (0.48) | FFAR1FFAR4MAOBGLAADAMTS4 | |
| SCHEMBL5290604 | 0.75 | GLA (0.43) | FFAR1FFAR4MAOBGLAADAMTS4 | |
| SCHEMBL2961510 | 0.72 | CYP2A6 (0.46) | MAOBMAOAMAPTKCNH2 | |
| SCHEMBL800275 | 0.70 | GLA (0.54) | FFAR1FFAR4MAOBGLAADAMTS4 | |
| SCHEMBL5691423 | 0.68 | AR (0.56) | FFAR1FFAR4 | |
| SCHEMBL24637979 | 0.67 | GLA (0.55) | FFAR1FFAR4MAOBGLACNR1 | |
| SCHEMBL3116723 | 0.67 | DAO (0.43) | ALDH1A1MAPT | |
| SCHEMBL20187649 | 0.67 | HRH3 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | disclosed |