SCHEMBL61636

SCHEMBL61636

CCCCCCCCCCCCCCCCCc1nc[nH]c1CCCCCCCCCCCCCCCCC.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.31
HRH4 Q9H3N8 1/20 0.31
PAK1 Q13153 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61792 1.00 HRH3 (0.31) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL727771 0.95
SCHEMBL21643905 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643894 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643899 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643983 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643903 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643916 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643895 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643913 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4722287-B2 2011-07-13 JP claimed
EP-1228109-B1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS DOW GLOBAL TECHNOLOGIES INC (US) 2006-02-01 EP claimed
US-6716786-B1 LEWIS ACIDS AND BASES THE DOW CHEMICAL COMPANY 2004-04-06 US claimed
US-6627573-B2 Useful as a cocatalyst for addition coordination polymerization comprising an anion containing at least two Lewis basic sites which are coordinated to Lewis acids, and further containing a hydroxyl group for support attachment THE DOW CHEMICAL COMPANY 2003-09-30 US claimed
EP-1056752-B1 Catalyst activators comprising expanded anions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-25 EP claimed
US-6462156-B2 AS POLYMERIZATION CATALYST FOR PRODUCING OLEFIN POLYMERS THE DOW CHEMICAL COMPANY 2002-10-08 US claimed
US-20020132729-A1 Catalyst activators comprising expanded anions LAPOINTE ROBERT E (US) 2002-09-19 US claimed
EP-1228109-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2002-08-07 EP claimed
US-6395671-B2 ANION CONTAINING TWO LEWIS BASIC SITES WHICH ARE COORDINATED TO LEWIS ACIDS; FOR OLEFIN POLYMERIZATION THE DOW CHEMICAL COMPANY 2002-05-28 US claimed
US-6376406-B1 COORDINATION POLYMERIZATION CATALYSTS FOR ALPHA-OLEFINS THE DOW CHEMICAL COMPANY 2002-04-23 US claimed
US-20020032120-A1 Expanded anionic compounds comprising hydroxyl or quiescent reactive functionality and catalyst activators therefrom DOW CHEMICAL COMPANY, THE 2002-03-14 US claimed
WO-2002008303-A1 EXPANDED ANIONIC COMPOUNDS COMPRISING HYDROXYL OR QUIESCENT REACTIVE FUNCTIONALITY AND CATALYST ACTIVATORS THEREFROM THE DOW CHEMICAL COMPANY (US) 2002-01-31 WO claimed
US-20010027161-A1 Catalyst activators comprising expanded anions THE DOW CHEMICAL COMPANY 2001-10-04 US claimed
WO-2001023442-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2001-04-05 WO claimed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP claimed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO claimed
EP-3519455-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-10 EP disclosed
EP-4234594-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2023-08-30 EP disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO disclosed