SCHEMBL61792

SCHEMBL61792

CCCCCCCCCCCc1nc[nH]c1CCCCCCCCCCC.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.31
HRH4 Q9H3N8 1/20 0.31
PAK1 Q13153 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61636 1.00 HRH3 (0.31) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL727771 0.95
SCHEMBL21643905 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643894 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643899 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643983 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643903 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643916 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643895 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A
SCHEMBL21643913 0.85 HRH3 (0.40) HRH3HRH4PAK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4722287-B2 2011-07-13 JP claimed
EP-1056752-B1 Catalyst activators comprising expanded anions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-25 EP claimed
US-6395671-B2 ANION CONTAINING TWO LEWIS BASIC SITES WHICH ARE COORDINATED TO LEWIS ACIDS; FOR OLEFIN POLYMERIZATION THE DOW CHEMICAL COMPANY 2002-05-28 US claimed
US-6376406-B1 COORDINATION POLYMERIZATION CATALYSTS FOR ALPHA-OLEFINS THE DOW CHEMICAL COMPANY 2002-04-23 US claimed
US-20010027161-A1 Catalyst activators comprising expanded anions THE DOW CHEMICAL COMPANY 2001-10-04 US claimed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP claimed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO claimed
EP-3519455-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-10 EP disclosed
EP-4234594-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2023-08-30 EP disclosed
EP-2024402-B2 HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-01-25 EP disclosed
US-20220204716-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC 2022-06-30 US disclosed
US-11359035-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
EP-1119575-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-08-01 EP disclosed
WO-2001046201-A1 GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-06-28 WO disclosed
WO-2001042315-A1 SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-06-14 WO disclosed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed
WO-2000020426-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-04-13 WO disclosed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204716-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS ACSL6, ELOVL6, ALOX5 HRH3 3980/4885HRH4 4116/4885PAK1 2279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.