Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.74 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.74 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164026 | 0.85 | SCN9A (0.63) | SCN4ASCN9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL29405312 | 0.85 | SCN4A (1.00) | SCN4ASCN9AKMT2AMEN1NPC1 | |
| SCHEMBL6164077 | 0.85 | SCN4A (1.00) | SCN4ASCN9AKMT2AMEN1NPC1 | |
| SCHEMBL30320026 | 0.85 | SCN4A (1.00) | SCN4ASCN9AKMT2AMEN1NPC1 | |
| SCHEMBL7921348 | 0.79 | SCN9A (0.65) | SCN4ASCN9AKMT2AMEN1NPC1 | |
| SCHEMBL17560984 | 0.79 | SCN4A (0.82) | SCN4ASCN9AKMT2AMEN1NPC1 | |
| SCHEMBL17560986 | 0.79 | SCN4A (0.82) | SCN4ASCN9AKMT2AMEN1NPC1 | |
| SCHEMBL6142385 | 0.78 | PDE4D (0.47) | SCN4ASCN9AMIFCRHBPCRHR2 | |
| SCHEMBL6165867 | 0.78 | SCN4A (0.75) | SCN4ASCN9AKMT2AMEN1NPC1 | |
| SCHEMBL17067808 | 0.78 | SCN4A (0.57) | SCN4ASCN9AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986540-B1 | THE USE OF CARBOCYCLIC AND HETEROCYCLIC SUBSTITUTED SEMICARBAZONES AND THIOSEMICARBAZONES AS SODIUM CHANNEL BLOCKERS | EURO CELTIQUE SA (LU) | 2005-02-16 | — | — | EP | claimed |