Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 16/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLD2 | O14939 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409743 | 0.93 | CALCRL (0.67) | CALCRLCYP3A4MEN1KMT2A | |
| SCHEMBL6163107 | 0.89 | CALCRL (0.64) | CALCRLCYP3A4PLD2PLD1RAMP1 | |
| Hydrochloric Acid SCHEMBL6162625 | 0.89 | CALCRL (0.63) | CALCRLCYP3A4PLD2PLD1RAMP1 | |
| SCHEMBL6160869 | 0.87 | CALCRL (0.58) | CALCRLCYP3A4MEN1KMT2APLD2 | |
| SCHEMBL6160874 | 0.87 | CALCRL (0.58) | CALCRLCYP3A4MEN1KMT2APLD2 | |
| SCHEMBL6163303 | 0.85 | CALCRL (0.58) | CALCRLCYP3A4MEN1KMT2A | |
| SCHEMBL6163308 | 0.85 | CALCRL (0.58) | CALCRLCYP3A4MEN1KMT2A | |
| SCHEMBL6160376 | 0.85 | CALCRL (0.66) | CALCRLCYP3A4RAMP1 | |
| SCHEMBL6160383 | 0.85 | CALCRL (0.66) | CALCRLCYP3A4RAMP1 | |
| Hydrochloric Acid SCHEMBL6163548 | 0.85 | CALCRL (0.57) | CALCRLCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |