Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 6/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | UGCG | Q16739 | 2/20 | 0.45 |
| ▸ | PLD2 | O14939 | 3/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160869 | 1.00 | CALCRL (0.58) | CALCRLDRD2DRD4SLC6A4HTR7 | |
| SCHEMBL8409743 | 0.93 | CALCRL (0.67) | CALCRLMEN1KMT2ACYP3A4CTSL | |
| SCHEMBL6159873 | 0.89 | CALCRL (0.64) | CALCRLDRD2DRD4SLC6A4HTR7 | |
| SCHEMBL6159881 | 0.89 | CALCRL (0.64) | CALCRLDRD2DRD4SLC6A4HTR7 | |
| SCHEMBL6163303 | 0.88 | CALCRL (0.58) | CALCRLMEN1KMT2ACYP3A4CTSL | |
| SCHEMBL6163308 | 0.88 | CALCRL (0.58) | CALCRLMEN1KMT2ACYP3A4CTSL | |
| Hydrochloric Acid SCHEMBL6163548 | 0.88 | CALCRL (0.57) | CALCRLMEN1KMT2ACYP3A4CTSL | |
| SCHEMBL6163706 | 0.87 | CALCRL (0.58) | CALCRLMEN1KMT2AAVPR1ACYP3A4 | |
| SCHEMBL6165816 | 0.86 | CALCRL (0.55) | CALCRLMEN1KMT2ACYP3A4CTSL | |
| SCHEMBL6165822 | 0.86 | CALCRL (0.55) | CALCRLMEN1KMT2ACYP3A4CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |