Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.66 |
| ▸ | DPP4 | P27487 | 2/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.58 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 8/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409646 | 1.00 | OPRD1 (0.66) | OPRD1DPP4DPP8DPP9UTS2R | |
| SCHEMBL3596301 | 0.83 | OPRD1 (0.61) | OPRD1DPP4DPP8DPP9CALCRL | |
| SCHEMBL3601983 | 0.83 | OPRD1 (0.61) | OPRD1DPP4DPP8DPP9CALCRL | |
| Hydrochloric Acid SCHEMBL3757142 | 0.82 | OPRD1 (0.60) | OPRD1DPP4DPP8DPP9CALCRL | |
| SCHEMBL6161491 | 0.81 | CALCRL (0.49) | OPRD1CALCRLF10CYP3A4 | |
| SCHEMBL6161500 | 0.81 | CALCRL (0.49) | OPRD1CALCRLF10CYP3A4 | |
| Hydrochloric Acid SCHEMBL6161553 | 0.81 | CALCRL (0.49) | OPRD1CALCRLF10CYP3A4 | |
| Hydrochloric Acid SCHEMBL6161544 | 0.81 | CALCRL (0.49) | OPRD1CALCRLF10CYP3A4 | |
| SCHEMBL27546866 | 0.79 | OPRD1 (0.47) | OPRD1DPP4DPP8DPP9UTS2R | |
| SCHEMBL4775337 | 0.79 | HDAC8 (0.58) | OPRD1DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |