Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CALCA | P06881 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163831 | 1.00 | CALCRL (0.47) | CALCRLCYP3A4BRD4LMNAFPR2 | |
| Hydrochloric Acid SCHEMBL6163658 | 0.99 | CALCRL (0.47) | CALCRLCYP3A4BRD4LMNAFPR2 | |
| Hydrochloric Acid SCHEMBL6163666 | 0.99 | CALCRL (0.47) | CALCRLCYP3A4BRD4LMNAFPR2 | |
| Hydrochloric Acid SCHEMBL6163290 | 0.89 | BRD4 (0.44) | CALCRLCYP3A4BRD4LMNAFPR2 | |
| Hydrochloric Acid SCHEMBL6163287 | 0.89 | BRD4 (0.44) | CALCRLCYP3A4BRD4LMNAFPR2 | |
| SCHEMBL6165473 | 0.86 | KMT2A (0.49) | CALCRLCYP3A4BRD4FPR2OPRM1 | |
| SCHEMBL6165477 | 0.86 | KMT2A (0.49) | CALCRLCYP3A4BRD4FPR2OPRM1 | |
| SCHEMBL6163764 | 0.86 | CALCRL (0.54) | CALCRLFPR2OPRM1KMT2AP2RY12 | |
| SCHEMBL6163760 | 0.86 | CALCRL (0.54) | CALCRLFPR2OPRM1KMT2AP2RY12 | |
| Hydrochloric Acid SCHEMBL6163192 | 0.85 | CALCRL (0.54) | CALCRLFPR2OPRM1KMT2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |