Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165473 | 1.00 | KMT2A (0.49) | KMT2AMAPK1PABPC1FPR2BRD4 | |
| SCHEMBL6162296 | 0.91 | FPR2 (0.41) | KMT2AMAPK1FPR2BRD4HRH2 | |
| SCHEMBL6162290 | 0.91 | FPR2 (0.41) | KMT2AMAPK1FPR2BRD4HRH2 | |
| SCHEMBL6165907 | 0.88 | MEN1 (0.51) | KMT2AFPR2CALCRLP2RY12MEN1 | |
| SCHEMBL6165912 | 0.88 | MEN1 (0.51) | KMT2AFPR2CALCRLP2RY12MEN1 | |
| SCHEMBL6163831 | 0.86 | CALCRL (0.47) | KMT2AFPR2BRD4OPRM1OPRD1 | |
| SCHEMBL6163841 | 0.86 | CALCRL (0.47) | KMT2AFPR2BRD4OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6163666 | 0.86 | CALCRL (0.47) | KMT2AFPR2BRD4OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6163658 | 0.86 | CALCRL (0.47) | KMT2AFPR2BRD4OPRM1OPRD1 | |
| SCHEMBL6162890 | 0.85 | MAPK1 (0.57) | KMT2AMAPK1PABPC1FPR2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |