Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.41 |
| ▸ | PPARA | Q07869 | 10/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164377 | 0.90 | PPARD (0.41) | PPARDPPARAPPARGHRH4HRH3 | |
| SCHEMBL6164763 | 0.86 | PPARD (0.59) | PPARDPPARAPPARG | |
| Hydrochloric Acid SCHEMBL5862770 | 0.86 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL6167418 | 0.81 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL6167228 | 0.80 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL6163710 | 0.80 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL6167938 | 0.80 | PPARD (0.41) | PPARDPPARAPPARG | |
| SCHEMBL6167073 | 0.79 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL6165253 | 0.79 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL5862769 | 0.78 | HRH3 (0.42) | HRH4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | claimed |