SCHEMBL6167938

SCHEMBL6167938

Cc1cc(SCc2cc(-c3ccc(C(F)(F)F)cc3)oc2CN(C)CCc2ccccc2)ccc1[O]

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.41
PPARA Q07869 8/20 0.41
PPARG P37231 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6167940 0.90 PPARD (0.40) PPARDPPARAPPARG
SCHEMBL6166880 0.87 PPARD (0.57) PPARDPPARAPPARG
Hydrochloric Acid SCHEMBL5861852 0.87 PPARD (0.56) PPARDPPARAPPARG
SCHEMBL6164052 0.86 PPARD (0.44) PPARDPPARAPPARG
SCHEMBL6168005 0.85 PPARD (0.39) PPARDPPARAPPARG
SCHEMBL5861914 0.84 PPARD (0.43) PPARDPPARAPPARG
SCHEMBL6164370 0.80 PPARD (0.41) PPARDPPARAPPARG
SCHEMBL6167418 0.79 PPARD (0.46) PPARDPPARAPPARG
SCHEMBL5862035 0.79 PRMT1 (0.40)
SCHEMBL6163710 0.79 PPARD (0.47) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392674-B1 FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS SMITHKLINE BEECHAM CORP (US) 2005-08-10 EP claimed