SCHEMBL6164435

SCHEMBL6164435

CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCC(c2ccc(F)cc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 10/20 0.53
OPRM1 P35372 1/20 0.52
CALCRL Q16602 1/20 0.48
ACE P12821 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
FPR2 P25090 1/20 0.48
PKM P14618 1/20 0.47
MMP3 P08254 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6164427 1.00 GHSR (0.53) GHSROPRM1CALCRLACEMEN1
Hydrochloric Acid SCHEMBL6161626 0.99 GHSR (0.52) GHSROPRM1CALCRLACEMEN1
Hydrochloric Acid SCHEMBL6165177 0.99 GHSR (0.52) GHSROPRM1CALCRLACEMEN1
SCHEMBL6160217 0.93 GHSR (0.55) GHSROPRM1CALCRLACEMEN1
SCHEMBL6160232 0.93 GHSR (0.55) GHSROPRM1CALCRLACEMEN1
SCHEMBL6161888 0.93 GHSR (0.51) GHSROPRM1CALCRLACEMEN1
SCHEMBL6161891 0.93 GHSR (0.51) GHSROPRM1CALCRLACEMEN1
Hydrochloric Acid SCHEMBL6161051 0.92 GHSR (0.54) GHSROPRM1CALCRLACEMEN1
Hydrochloric Acid SCHEMBL6161057 0.92 GHSR (0.54) GHSROPRM1CALCRLACEMEN1
Hydrochloric Acid SCHEMBL6161101 0.92 GHSR (0.51) GHSROPRM1CALCRLACEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed