Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.58 |
| ▸ | HTR6 | P50406 | 7/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638482 | 0.78 | HTR2C (0.69) | HTR2CHTR6SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6075674 | 0.76 | HTR2C (0.70) | HTR2CHTR6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6160494 | 0.76 | SLC6A2 (0.53) | HTR2CHTR6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3121349 | 0.74 | HTR2C (0.56) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL5584737 | 0.74 | HTR2C (1.00) | HTR2CHTR6SLC6A2SLC6A4HTR1A | |
| SCHEMBL20494904 | 0.73 | HTR2C (0.51) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20368608 | 0.73 | HTR2C (0.57) | HTR2C | |
| Hydrochloric Acid SCHEMBL21855666 | 0.73 | HTR2C (1.00) | HTR2CHTR6SLC6A2SLC6A4HTR1A | |
| Hydrochloric Acid SCHEMBL31109384 | 0.73 | HTR2C (1.00) | HTR2CHTR6SLC6A2SLC6A4HTR1A | |
| SCHEMBL24120164 | 0.71 | HTR2C (0.69) | HTR2CHTR6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |