Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.69 |
| ▸ | HTR6 | P50406 | 8/20 | 0.58 |
| ▸ | HTR1A | P08908 | 8/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6075674 | 0.98 | HTR2C (0.70) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| SCHEMBL19633961 | 0.87 | HTR2C (0.48) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| SCHEMBL5584737 | 0.81 | HTR2C (1.00) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| SCHEMBL3765929 | 0.81 | HTR1A (0.58) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| SCHEMBL30368779 | 0.81 | HTR1A (0.61) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL233327 | 0.81 | HTR1A (0.61) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL21855666 | 0.80 | HTR2C (1.00) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL31109384 | 0.80 | HTR2C (1.00) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4893603 | 0.80 | HTR1A (0.56) | HTR2CHTR6HTR1ASLC6A2SLC6A4 | |
| SCHEMBL741486 | 0.80 | HTR2C (0.43) | HTR2CHTR6HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432701-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2004-06-30 | — | — | EP | claimed |
| WO-2003031436-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. (CH) | 2003-04-17 | — | — | WO | claimed |
| EP-2220083-B1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | JANSSEN PHARMACEUTICALS INC (US) | 2017-07-19 | — | — | EP | disclosed |