SCHEMBL6164889

SCHEMBL6164889

COc1c(O)cc(C)c(CCCc2c(C)cc(O)c(OC)c2C)c1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.45
TDP1 Q9NUW8 1/20 0.43
APP P05067 1/20 0.38
IMPDH2 P12268 1/20 0.38
CYP3A4 P08684 2/20 0.38
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36
TUBB4B P68371 2/20 0.36
TUBB3 Q13509 2/20 0.36
TUBB2A Q13885 2/20 0.36
TUBB8 Q3ZCM7 2/20 0.36
TUBA3E Q6PEY2 2/20 0.36
TUBA1A Q71U36 2/20 0.36
TUBA1C Q9BQE3 2/20 0.36
TUBB6 Q9BUF5 2/20 0.36
TUBB2B Q9BVA1 2/20 0.36
TUBB1 Q9H4B7 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6166131 0.94 TDP1 (0.45) ALOX5TDP1APPIMPDH2CYP3A4
SCHEMBL19463397 0.89 ALOX5 (0.46) ALOX5TDP1APPIMPDH2CYP3A4
SCHEMBL68787 0.86 TDP1 (0.45) ALOX5TDP1APPIMPDH2CYP3A4
SCHEMBL29659488 0.86 TDP1 (0.45) ALOX5TDP1APPIMPDH2CYP3A4
SCHEMBL19464017 0.85 TDP1 (0.43) ALOX5TDP1APPIMPDH2CYP3A4
SCHEMBL3141949 0.79 CYP3A4 (0.41) ALOX5TDP1APPIMPDH2CYP3A4
SCHEMBL4622981 0.77 TDP1 (0.52) ALOX5TDP1IMPDH2CYP3A4TUBB1
SCHEMBL28272590 0.77 TDP1 (0.52) ALOX5TDP1IMPDH2CYP3A4MAPT
SCHEMBL17773091 0.75 TDP1 (0.50) ALOX5TDP1CYP3A4MAPTMEN1
SCHEMBL10008427 0.75 TDP1 (0.50) ALOX5TDP1IMPDH2CYP3A4TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138719-B1 POLYIMIDE/POLYARYLATE RESIN COMPOSITIONS AND MOLDINGS THEREOF TEIJIN LTD (JP) 2005-02-16 EP disclosed
US-6610794-B1 Excellent heat resistance, moldability, dimensional stability and transparency TEIJIN LIMITED (JP) 2003-08-26 US disclosed
EP-1138719-A1 POLYIMIDE/POLYARYLATE RESIN COMPOSITIONS AND MOLDINGS THEREOF TEIJIN LIMITED (JP) 2001-10-04 EP disclosed