Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164964 | 1.00 | CALCRL (0.54) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6161647 | 0.87 | CALCRL (0.56) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6161231 | 0.87 | CALCRL (0.56) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3635261 | 0.83 | CHRM1 (0.72) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| Trifluoroacetic Acid SCHEMBL6161823 | 0.82 | CALCRL (0.53) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| Trifluoroacetic Acid SCHEMBL6162047 | 0.82 | CALCRL (0.53) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6165662 | 0.82 | CALCRL (0.55) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6165656 | 0.82 | CALCRL (0.55) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8863501 | 0.80 | CHRM1 (0.79) | CALCRLCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22716847 | 0.79 | CHRM1 (0.63) | CALCRLCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |