Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 6/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PLD2 | O14939 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161647 | 1.00 | CALCRL (0.56) | CALCRLOPRL1OPRM1OPRK1CHRM2 | |
| Trifluoroacetic Acid SCHEMBL6161823 | 0.95 | CALCRL (0.53) | CALCRLOPRL1OPRM1OPRK1CHRM2 | |
| Trifluoroacetic Acid SCHEMBL6162047 | 0.95 | CALCRL (0.53) | CALCRLOPRL1OPRM1OPRK1CHRM2 | |
| SCHEMBL6164964 | 0.87 | CALCRL (0.54) | CALCRLOPRL1OPRM1OPRK1CHRM2 | |
| SCHEMBL6164957 | 0.87 | CALCRL (0.54) | CALCRLOPRL1OPRM1OPRK1CHRM2 | |
| SCHEMBL6163603 | 0.83 | CALCRL (0.59) | CALCRLCYP3A4HSD11B1 | |
| SCHEMBL6161636 | 0.83 | CALCRL (0.59) | CALCRLCYP3A4HSD11B1 | |
| SCHEMBL6161820 | 0.82 | CALCRL (0.58) | CALCRLOPRL1OPRM1OPRK1CYP3A4 | |
| SCHEMBL6162042 | 0.82 | CALCRL (0.58) | CALCRLOPRL1OPRM1OPRK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6160811 | 0.82 | CALCRL (0.58) | CALCRLCYP3A4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |