Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6161743 | 0.92 | F2 (0.50) | F10PRSS1F2HPGDSPLG | |
| SCHEMBL15893668 | 0.80 | PRSS1 (0.55) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL15810860 | 0.79 | CTSS (0.61) | HPGDS | |
| SCHEMBL6248471 | 0.79 | CTSS (0.61) | HPGDS | |
| SCHEMBL15810862 | 0.79 | CTSS (0.61) | HPGDS | |
| Hydrochloric Acid SCHEMBL5274210 | 0.78 | PRSS1 (0.54) | F10PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL5672707 | 0.76 | SLC7A5 (0.58) | F10PRSS1F2PLG | |
| SCHEMBL18069355 | 0.76 | F10 (0.56) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL202409 | 0.76 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL288337 | 0.76 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | claimed |