SCHEMBL6165426

SCHEMBL6165426

Oc1ccc(CCCc2ccc(O)cc2Cl)c(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
TYR P14679 3/20 0.48
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX5 P09917 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TTR P02766 1/20 0.45
BACE1 P56817 1/20 0.43
ESR1 P03372 6/20 0.42
ESR2 Q92731 4/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4208352 0.91 TYR (0.58) HSD17B10TYRMEN1MAPTKMT2A
SCHEMBL11655822 0.88 TYR (0.67) HSD17B10TYRMEN1MAPTKMT2A
SCHEMBL27763432 0.85 CYP3A4 (0.69) HSD17B10TYRMEN1MAPTKMT2A
SCHEMBL14793793 0.85 F13A1 (0.46)
SCHEMBL10645495 0.85 CYP3A4 (0.69) HSD17B10TYRMEN1MAPTKMT2A
SCHEMBL16355887 0.83 IGF1R (0.47) ALOX5ALOX15
SCHEMBL3767315 0.83 TAAR1 (0.52) HSD17B10TYRMEN1MAPTKMT2A
SCHEMBL6577495 0.83 HSD17B10 (0.48) HSD17B10TYRMEN1MAPTKMT2A
SCHEMBL9565680 0.83 TYR (0.50) HSD17B10TYRMEN1MAPTKMT2A
SCHEMBL16355886 0.82 IGF1R (0.46) ALOX5ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138719-B1 POLYIMIDE/POLYARYLATE RESIN COMPOSITIONS AND MOLDINGS THEREOF TEIJIN LTD (JP) 2005-02-16 EP disclosed
US-6610794-B1 Excellent heat resistance, moldability, dimensional stability and transparency TEIJIN LIMITED (JP) 2003-08-26 US disclosed
EP-1138719-A1 POLYIMIDE/POLYARYLATE RESIN COMPOSITIONS AND MOLDINGS THEREOF TEIJIN LIMITED (JP) 2001-10-04 EP disclosed