Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29786713 | 0.85 | MAPT (0.74) | MAPTGAAABCB11LMNAPTGS1 | |
| Benzene SCHEMBL28303083 | 0.85 | MAPT (0.74) | MAPTGAAABCB11LMNAPTGS1 | |
| SCHEMBL112508 | 0.85 | MAPT (0.74) | MAPTGAAABCB11LMNAPTGS1 | |
| SCHEMBL28282156 | 0.83 | MAPT (0.71) | MAPTGAAABCB11LMNAPTGS1 | |
| SCHEMBL8586971 | 0.80 | MAPT (0.46) | MAPTGAANPC1RAB9AALDH1A1 | |
| SCHEMBL9706058 | 0.80 | GAA (0.55) | MAPTGAAABCB11LMNAPTGS1 | |
| SCHEMBL8586968 | 0.80 | MAPT (0.49) | MAPTGAANPC1RAB9AALDH1A1 | |
| SCHEMBL9737659 | 0.78 | LIG1 (0.56) | MAPTGAARAB9AABCB11LMNA | |
| SCHEMBL14124710 | 0.78 | AKR1C3 (0.68) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29041025 | 0.78 | MAPT (0.62) | MAPTGAANPC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842212-B1 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NASA (US) | 2005-02-16 | — | — | EP | disclosed |