Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737105 | 0.87 | MAPT (0.61) | MAPTGAASRD5A2BCL2MCL1 | |
| SCHEMBL9859607 | 0.84 | MAPT (0.61) | MAPTGAASRD5A2BCL2MCL1 | |
| SCHEMBL7542589 | 0.83 | CTNNB1 (0.47) | MAPTGAASRD5A2BCL2MCL1 | |
| SCHEMBL31372448 | 0.81 | CTNNB1 (0.46) | MAPTGAASRD5A2BCL2MCL1 | |
| SCHEMBL28482644 | 0.81 | CTNNB1 (0.46) | MAPTGAASRD5A2BCL2MCL1 | |
| SCHEMBL6165445 | 0.80 | MAPT (0.54) | MAPTGAANPC1RAB9AKDM4E | |
| SCHEMBL10390477 | 0.80 | AKR1C3 (0.60) | MAPTGAASRD5A2BCL2MCL1 | |
| SCHEMBL6162870 | 0.79 | CTNNB1 (0.53) | MAPTSRD5A2BCL2MCL1BAD | |
| SCHEMBL8586968 | 0.78 | MAPT (0.49) | MAPTGAANPC1RAB9AFFAR1 | |
| SCHEMBL25135304 | 0.78 | MAPT (0.50) | MAPTHAO1NPC1FFAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842212-A4 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NASA (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0842212-A1 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006200-A1 | IMIDE OLIGOMERS AND CO-OLIGOMERS CONTAINING PENDENT PHENYLETHYNYL GROUPS AND POLYMERS THEREFROM | NATIONAL AERONAUTICS & SPACE ADMINISTRATION (US) | 1997-02-20 | — | — | WO | disclosed |