SCHEMBL616591

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL615990	0.91	MAPT (0.49)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL618320	0.89	MAPT (0.48)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL617849	0.89	MAPT (0.48)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL617868	0.89	MAPT (0.53)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL617970	0.89	MAPT (0.62)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL618662	0.86	MAPT (0.46)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL615937	0.86	MAPT (0.46)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL616413	0.86	MAPT (0.46)	KMT2AMEN1MAPTMAPK1ATM
	SCHEMBL618742	0.79	MEN1 (0.40)	KMT2AMEN1GAALMNAHSP90AA1
	SCHEMBL1167653	0.79	MEN1 (0.63)	KMT2AMEN1MAPTMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.