Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465492 | 0.88 | ALDH1A1 (0.63) | NPC1ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL11078052 | 0.88 | NPC1 (0.57) | NPC1ALDH1A1RAB9ACYP1A2MAPT | |
| SCHEMBL14569637 | 0.85 | MAPT (0.51) | NPC1ALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL11775547 | 0.85 | ALDH1A1 (0.49) | NPC1ALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL11775543 | 0.85 | ALDH1A1 (0.49) | NPC1ALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL11775551 | 0.84 | NPC1 (0.51) | NPC1ALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL11636740 | 0.84 | MAPT (0.54) | NPC1ALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL11528622 | 0.84 | MAPT (0.54) | NPC1ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL9172922 | 0.82 | NPC1 (0.51) | NPC1ALDH1A1RAB9AMAPTLMNA | |
| SCHEMBL3139745 | 0.82 | NPC1 (0.51) | NPC1ALDH1A1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711758-B1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-1020450-A1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |