Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166097 | 0.93 | IKBKB (0.38) | ALOX5APFEN1IKBKBF2PRSS1 | |
| SCHEMBL7104633 | 0.73 | F10 (0.46) | MEN1KMT2ATP53ATRF2 | |
| SCHEMBL6164926 | 0.66 | F10 (0.51) | MEN1KMT2AATRF2PRSS1 | |
| SCHEMBL25439559 | 0.65 | GAA (0.47) | MEN1KMT2AALDH1A1IKBKBBRD4 | |
| SCHEMBL5734930 | 0.64 | BAZ2B (0.41) | ALOX5APFEN1BAZ2BBAZ2AALDH1A1 | |
| SCHEMBL3829742 | 0.61 | BAZ2B (0.40) | ALOX5APFEN1BAZ2BBAZ2AMEN1 | |
| SCHEMBL5724281 | 0.60 | ALOX5AP (0.43) | ALOX5APFEN1BAZ2BBAZ2ABRD9 | |
| SCHEMBL9862600 | 0.58 | BAZ2B (0.42) | ALOX5APFEN1BAZ2BBAZ2AALDH1A1 | |
| SCHEMBL5171111 | 0.58 | BAZ2B (0.50) | BAZ2BBAZ2AKMT2ABRD9BRD4 | |
| SCHEMBL15407008 | 0.58 | MKNK1 (0.43) | ALOX5APFEN1BAZ2BBAZ2ABRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |