Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168010 | 0.82 | PPARD (0.40) | HIF1AEPAS1ACHEMAOBCYP3A4 | |
| SCHEMBL5862035 | 0.81 | PRMT1 (0.40) | CYP3A4CYP2C19SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL6168005 | 0.80 | PPARD (0.39) | HIF1AEPAS1ACHEMAOBCYP3A4 | |
| SCHEMBL5860726 | 0.80 | TACR1 (0.38) | ACHEMAOBSMN1; SMN2NPC1BCHE | |
| Hydrochloric Acid SCHEMBL5861139 | 0.77 | PPARD (0.55) | — | |
| SCHEMBL27602785 | 0.76 | HIF1A (0.65) | HIF1AEPAS1CYP3A4MAPK1CHRNB2 | |
| SCHEMBL6162606 | 0.76 | CYP3A4 (0.41) | HIF1AEPAS1CYP3A4CYP2C19NR1H2 | |
| SCHEMBL5860888 | 0.75 | PPARD (0.43) | — | |
| SCHEMBL5861037 | 0.75 | PRMT1 (0.37) | CYP3A4CYP2C19 | |
| SCHEMBL5860604 | 0.75 | S1PR1 (0.42) | MAOBCYP3A4CYP2C19SMN1; SMN2SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |