Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.44 |
| ▸ | PPARA | Q07869 | 10/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861193 | 0.92 | NPC1 (0.38) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5861817 | 0.92 | PPARD (0.49) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5861885 | 0.85 | PPARD (0.49) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5861813 | 0.84 | PPARD (0.58) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5860603 | 0.82 | PPARD (0.51) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5861827 | 0.81 | PPARD (0.48) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5861828 | 0.81 | PPARD (0.49) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5860825 | 0.81 | PPARD (0.51) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5860849 | 0.80 | PPARD (0.51) | PPARDPPARAPTGDR2PPARG | |
| SCHEMBL5861095 | 0.80 | PPARA (0.50) | PPARDPPARAPTGDR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |