Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 4/20 | 0.51 |
| ▸ | MC5R | P33032 | 3/20 | 0.51 |
| ▸ | MC3R | P41968 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200374 | 1.00 | ALPI (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL9872582 | 0.87 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2015825 | 0.85 | SLC7A5 (0.59) | SLC7A5MC4RMC5RMC3RHDAC8 | |
| SCHEMBL2015826 | 0.85 | SLC7A5 (0.59) | SLC7A5MC4RMC5RMC3RHDAC8 | |
| SCHEMBL26518995 | 0.85 | ALPI (0.58) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL26871861 | 0.84 | ALPI (0.46) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL5605249 | 0.84 | SLC7A5 (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL24785636 | 0.84 | MC4R (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1764633 | 0.82 | ALPI (0.63) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL30959049 | 0.82 | ALPI (0.63) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134213-B1 | Process for the preparation of substituted N-(indole-2-carbonyl)- glycinamides | PFIZER (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-0832065-B1 | SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1134213-A2 | Process for the preparation of substituted N-(indole-2-carbonyl)- glycinamides | PFIZER INC. (US) | 2001-09-19 | — | — | EP | disclosed |
| US-6277877-B1 | GLYCOGEN PHOSPHORYLASE INHIBITOR; ANTIDIABETIC AGENTS | PFIZER, INC. | 2001-08-21 | — | — | US | disclosed |
| US-6107329-A | HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS | PFIZER, INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0495013-B1 | HEXAPEPTIDES WITH SULPHATE ESTER GROUPS | FISONS CORP (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0226217-B1 | Peptides with sulfate ester group | FISONS CORP (US) | 1994-01-26 | — | — | EP | disclosed |
| EP-0495013-A1 | HEXAPEPTIDES WITH SULPHATE ESTER GROUPS. | FISONS CORP (US) | 1992-07-22 | — | — | EP | disclosed |
| WO-1991008225-A1 | HEXAPEPTIDES WITH SULPHATE ESTER GROUPS | FISONS CORPORATION (US) | 1991-06-13 | — | — | WO | disclosed |