Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 4/20 | 0.52 |
| ▸ | MC5R | P33032 | 3/20 | 0.52 |
| ▸ | MC3R | P41968 | 3/20 | 0.52 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785636 | 0.91 | MC4R (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Hydrochloric Acid SCHEMBL9439526 | 0.88 | MC4R (0.57) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8917376 | 0.88 | MC4R (0.60) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL6166496 | 0.87 | ALPI (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL9200374 | 0.87 | ALPI (0.59) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL28185552 | 0.86 | SLC7A5 (0.56) | SLC7A5MC4RMC5RMC3RHDAC8 | |
| SCHEMBL28185553 | 0.86 | SLC7A5 (0.56) | SLC7A5MC4RMC5RMC3RHDAC8 | |
| SCHEMBL9572329 | 0.83 | MC4R (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL5605249 | 0.81 | SLC7A5 (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7500822 | 0.81 | SLC1A1 (0.51) | TP53SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |