Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 3/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166633 | 1.00 | KDM4E (0.48) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27493871 | 1.00 | KDM4E (0.48) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2081773 | 0.90 | KDM4E (0.44) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2081775 | 0.90 | KDM4E (0.44) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27533526 | 0.90 | KDM4E (0.44) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2744582 | 0.84 | KDM4E (0.59) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29766836 | 0.84 | KDM4E (0.59) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL500694 | 0.84 | KDM4E (0.51) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6662420 | 0.84 | KDM4E (0.51) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9096418 | 0.84 | KDM4E (0.51) | KDM4ECYP1A2SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134219-B1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6573260-B1 | Antibiotics | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1134219-A1 | CYCLOALKYL-SUBSTITUTED AMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |