Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | TOP2A | P11388 | 6/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766836 | 1.00 | KDM4E (0.59) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6004997 | 0.99 | KDM4E (0.57) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| SCHEMBL28458144 | 0.99 | KDM4E (0.57) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL3808640 | 0.94 | KDM4E (0.53) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| SCHEMBL9146620 | 0.89 | KDM4E (0.59) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| SCHEMBL29518174 | 0.88 | MEN1 (0.60) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| SCHEMBL22506561 | 0.88 | HTR3A (0.47) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| Potassium Ion SCHEMBL22497604 | 0.87 | KDM4E (0.44) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| SCHEMBL24616680 | 0.85 | HTR3A (0.47) | KDM4ETOP2ATOP2BALDH1A1LMNA | |
| SCHEMBL6166633 | 0.84 | KDM4E (0.48) | KDM4ETOP2ATOP2BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101068821-A | Hybrid QA molecules where Q is an aminoquinoline and A is an antibiotic residue, their synthesis and use as antibacterial agents | PALUMED SA (FR) | 2007-11-07 | — | — | CN | claimed |
| EP-0169993-B1 | 7-(3-ARYL-1-PIPERAZINYL) AND 7-(3-CYCLOHEXYL-1-PIPERAZINYL) 3-QUINOLINE CARBOXYLIC ACIDS | BAYER AG (DE) | 1988-12-28 | — | — | EP | claimed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | claimed |
| EP-3929180-B1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE IND CO LTD (CN) | 2026-03-04 | — | — | EP | disclosed |
| US-20250313533-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2025-10-09 | — | — | US | disclosed |
| US-11970487-B1 | 7-(4-((5-(benzylideneamino)-2-thioxo-1,3,4-thiadiazol-3(2h)-yl)methyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid as an anti-inflammatory and anticancer compound | King Faisal University (SA) | 2024-04-30 | — | — | US | disclosed |
| US-11873299-B1 | 7-(4-((5-(4-chlorobenzylideneamino)-2-thioxo-1,3,4-thiadiazol-3(2H)-yl)methyl)iperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid as an anti-inflammatory compound | King Faisal University (SA) | 2024-01-16 | — | — | US | disclosed |
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| US-11261205-B2 | Oxazolidinone-quinolone hybrid antibacterial for the parenteral treatment of prophylaxis of bacterial diseases | MORPHOCHEM GMBH (DE) | 2022-03-01 | — | — | US | disclosed |
| EP-3929180-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shandong United Pesticide Industry Co., Ltd. (CN) | 2021-12-29 | — | — | EP | disclosed |
| EP-0641793-A1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5300644-A | Process for the preparation of quinoline carboxylic acids | CHINOIN GYOGYSER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1994-04-05 | — | — | US | disclosed |
| CN-1074218-A | Quinolone-and naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1993-07-14 | — | — | CN | disclosed |
| EP-0237955-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5091530-A | BARON CHELATES OF QUINOLINE CARBOXYLIC ACIDS | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1992-02-25 | — | — | US | disclosed |
| CN-88101907-A | Process for preparing quinoline carboxylic acids | — | 1988-10-26 | — | — | CN | disclosed |
| CN-85101832-A | The method for preparing 7-(3-aryl-1-piperazinyl)-3-quinolone carboxylic acid and 7-(3-encircles ethyl-1-piperazinyl)-3-quinolone carboxylic acid | — | 1987-01-31 | — | — | CN | disclosed |
| EP-0113092-B1 | 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(4-(OXOALKYL)-1-PIPERAZINYL)-3-QUINOLINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1986-05-21 | — | — | EP | disclosed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313533-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | NAAA, SDHA, GLUL | KDM4E 858/4885TOP2A 681/4885TOP2B 930/4885 |
| US-11873299-B1 | 7-(4-((5-(4-chlorobenzylideneamino)-2-thioxo-1,3,4-thiadiazol-3(2H)-yl)methyl)iperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid as an anti-inflammatory compound | DPP4, IL1A, IL1B | KDM4E 881/4885TOP2A 255/4885TOP2B 553/4885 |
| US-11970487-B1 | 7-(4-((5-(benzylideneamino)-2-thioxo-1,3,4-thiadiazol-3(2h)-yl)methyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid as an anti-inflammatory and anticancer compound | IL1A, NFKBIA, CASP1 | KDM4E 1046/4885TOP2A 34/4885TOP2B 68/4885 |
| US-11261205-B2 | Oxazolidinone-quinolone hybrid antibacterial for the parenteral treatment of prophylaxis of bacterial diseases | NQO2, QARS1, RECQL | KDM4E 4487/4885TOP2A 56/4885TOP2B 85/4885 |
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SDHA, GLUL, PGLS | KDM4E 1227/4885TOP2A 169/4885TOP2B 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.