Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.72 |
| ▸ | FNTB | P49356 | 13/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.59 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161541 | 0.94 | FNTA (0.75) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL6162034 | 0.93 | FNTA (0.74) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL7673444 | 0.89 | FNTA (0.58) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL7665450 | 0.85 | FNTA (0.72) | FNTAFNTBCYP3A4PGGT1B | |
| Tipifarnib SCHEMBL23633189 | 0.84 | FNTA (0.80) | FNTAFNTBCYP3A4PGGT1B | |
| (S)-Tipifarnib SCHEMBL4429738 | 0.84 | FNTA (0.80) | FNTAFNTBCYP3A4PGGT1B | |
| Tipifarnib SCHEMBL21544535 | 0.84 | FNTA (0.80) | FNTAFNTBCYP3A4PGGT1B | |
| Tipifarnib SCHEMBL22772860 | 0.84 | FNTA (0.80) | FNTAFNTBCYP3A4PGGT1B | |
| Tipifarnib SCHEMBL8097 | 0.84 | FNTA (0.80) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL11947168 | 0.84 | FNTA (1.00) | FNTAFNTBCYP3A4PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107962-B1 | QUINOLIN-2-ONE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PROD INC (US) | 2005-02-23 | — | — | EP | disclosed |